TY - GEN AU - Jost,Marco AU - Santos,Daniel A AU - Saunders,Reuben A AU - Horlbeck,Max A AU - Hawkins,John S AU - Scaria,Sonia M AU - Norman,Thomas M AU - Hussmann,Jeffrey A AU - Liem,Christina R AU - Gross,Carol A AU - Weissman,Jonathan S TI - Titrating gene expression using libraries of systematically attenuated CRISPR guide RNAs SN - 1546-1696 PY - 2020///0410 KW - CRISPR-Cas Systems KW - Computational Biology KW - methods KW - Deep Learning KW - Gene Editing KW - Gene Expression KW - Genomic Library KW - HeLa Cells KW - Humans KW - K562 Cells KW - Phenotype KW - RNA, Guide, CRISPR-Cas Systems KW - genetics KW - Sequence Analysis, RNA KW - Single-Cell Analysis N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/s41587-019-0387-5 ER -