TY - GEN AU - Smith,Heather L AU - Freeman,Oliver J AU - Butcher,Adrian J AU - Holmqvist,Staffan AU - Humoud,Ibrahim AU - Schätzl,Tobias AU - Hughes,Daniel T AU - Verity,Nicholas C AU - Swinden,Dean P AU - Hayes,Joseph AU - de Weerd,Lis AU - Rowitch,David H AU - Franklin,Robin J M AU - Mallucci,Giovanna R TI - Astrocyte Unfolded Protein Response Induces a Specific Reactivity State that Causes Non-Cell-Autonomous Neuronal Degeneration SN - 1097-4199 PY - 2020///0707 KW - Animals KW - Astrocytes KW - metabolism KW - Endoplasmic Reticulum Stress KW - drug effects KW - Enzyme Inhibitors KW - pharmacology KW - Eukaryotic Initiation Factor-2B KW - In Vitro Techniques KW - Memory KW - Mice KW - Neurodegenerative Diseases KW - Phosphorylation KW - Prion Diseases KW - Protein Biosynthesis KW - Protein Phosphatase 1 KW - genetics KW - Signal Transduction KW - Synapses KW - Thapsigargin KW - Transcriptome KW - Tunicamycin KW - Unfolded Protein Response KW - eIF-2 Kinase N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.neuron.2019.12.014 ER -