TY - GEN AU - Scarneo,Scott A AU - Hughes,Philip F AU - Yang,Kelly W AU - Carlson,David A AU - Gurbani,Deepak AU - Westover,Kenneth D AU - Haystead,Timothy A J TI - A highly selective inhibitor of interleukin-1 receptor-associated kinases 1/4 (IRAK-1/4) delineates the distinct signaling roles of IRAK-1/4 and the TAK1 kinase SN - 1083-351X PY - 2020///1014 KW - Benzamides KW - pharmacology KW - Benzimidazoles KW - Humans KW - Interleukin-1 Receptor-Associated Kinases KW - antagonists & inhibitors KW - Lipopolysaccharides KW - immunology KW - MAP Kinase Kinase Kinases KW - Models, Molecular KW - Protein Kinase Inhibitors KW - Signal Transduction KW - drug effects KW - Synoviocytes KW - THP-1 Cells N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1074/jbc.RA119.011857 ER -