TY - GEN AU - Dai,Shaobo AU - Horton,John R AU - Wilkinson,Alex W AU - Gozani,Or AU - Zhang,Xing AU - Cheng,Xiaodong TI - An engineered variant of SETD3 methyltransferase alters target specificity from histidine to lysine methylation SN - 1083-351X PY - 2020///1021 KW - Actins KW - metabolism KW - Amino Acid Substitution KW - Catalytic Domain KW - Histidine KW - Histone Methyltransferases KW - chemistry KW - Histone-Lysine N-Methyltransferase KW - genetics KW - Humans KW - Hydrogen Bonding KW - Lysine KW - Methylation KW - Protein Engineering KW - Substrate Specificity N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1074/jbc.RA119.012319 ER -