Scott, Helen L

A dual druggable genome-wide siRNA and compound library screening approach identifies modulators of parkin recruitment to mitochondria. [electronic resource] - The Journal of biological chemistry 03 2020 - 3285-3300 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1083-351X

10.1074/jbc.RA119.009699 doi


Benzazepines--chemistry
HeLa Cells
Humans
Hydrazones--chemistry
Indoles--chemistry
Membrane Potential, Mitochondrial--drug effects
Mitochondria--metabolism
Mitophagy--drug effects
Principal Component Analysis
Protein Kinases--chemistry
RNA Interference
RNA, Small Interfering--metabolism
Small Molecule Libraries--chemistry
Ubiquitin-Conjugating Enzymes--antagonists & inhibitors
Ubiquitin-Protein Ligases--antagonists & inhibitors