TY - GEN AU - Thomaidou,Sofia AU - Kracht,Maria J L AU - van der Slik,Arno AU - Laban,Sandra AU - de Koning,Eelco J AU - Carlotti,Francoise AU - Hoeben,Rob C AU - Roep,Bart O AU - Zaldumbide,Arnaud TI - β-Cell Stress Shapes CTL Immune Recognition of Preproinsulin Signal Peptide by Posttranscriptional Regulation of Endoplasmic Reticulum Aminopeptidase 1 SN - 1939-327X PY - 2020///0803 KW - Aminopeptidases KW - genetics KW - CD8-Positive T-Lymphocytes KW - drug effects KW - Down-Regulation KW - Endoplasmic Reticulum Stress KW - Endoribonucleases KW - HEK293 Cells KW - Humans KW - Inflammation KW - Insulin KW - metabolism KW - Insulin-Secreting Cells KW - Interferon-gamma KW - pharmacology KW - Interleukin-1beta KW - MicroRNAs KW - Minor Histocompatibility Antigens KW - Protein Precursors KW - Protein Serine-Threonine Kinases KW - Up-Regulation N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.2337/db19-0984 ER -