TY  - GEN
AU  - Ng,Sheng Rong
AU  - Rideout,William M
AU  - Akama-Garren,Elliot H
AU  - Bhutkar,Arjun
AU  - Mercer,Kim L
AU  - Schenkel,Jason M
AU  - Bronson,Roderick T
AU  - Jacks,Tyler
TI  - CRISPR-mediated modeling and functional validation of candidate tumor suppressor genes in small cell lung cancer
SN  - 1091-6490
PY  - 2020///0505
KW  - Animals
KW  - Apoptosis
KW  - genetics
KW  - CRISPR-Cas Systems
KW  - Cell Line
KW  - Cell Proliferation
KW  - Disease Models, Animal
KW  - Disease Progression
KW  - Feasibility Studies
KW  - Gene Editing
KW  - methods
KW  - Gene Expression Regulation, Neoplastic
KW  - Genes, Tumor Suppressor
KW  - Humans
KW  - Loss of Function Mutation
KW  - Lung
KW  - pathology
KW  - Lung Neoplasms
KW  - Mice
KW  - Mice, Transgenic
KW  - Neoplasm Staging
KW  - Retinoblastoma-Like Protein p107
KW  - Retinoblastoma-Like Protein p130
KW  - Small Cell Lung Carcinoma
KW  - Tumor Burden
KW  - Tumor Suppressor Protein p53
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1073/pnas.1821893117
ER  -