Erythropoiesis defect observed in STAT3 GOF patients with severe anemia. [electronic resource]
- The Journal of allergy and clinical immunology 04 2020
- 1297-1301 p. digital
Publication Type: Letter; Research Support, Non-U.S. Gov't
1097-6825
10.1016/j.jaci.2019.11.042 doi
Anemia, Hemolytic, Autoimmune--drug therapy Asthma--genetics Cell Differentiation Cell Proliferation Cells, Cultured Child Erythrocytes--physiology Erythropoiesis--genetics Erythropoietin--metabolism Gene Expression Regulation Germ-Line Mutation--genetics Humans Iron Chelating Agents--therapeutic use Receptors, Erythropoietin--metabolism STAT3 Transcription Factor--genetics STAT5 Transcription Factor--metabolism Severity of Illness Index Signal Transduction Exome Sequencing beta-Globins--genetics