TY  - GEN
AU  - Stevens,Alexandra M
AU  - Xiang,Michael
AU  - Heppler,Lisa N
AU  - Tošić,Isidora
AU  - Jiang,Kevin
AU  - Munoz,Jaime O
AU  - Gaikwad,Amos S
AU  - Horton,Terzah M
AU  - Long,Xin
AU  - Narayanan,Padmini
AU  - Seashore,Elizabeth L
AU  - Terrell,Maci C
AU  - Rashid,Raushan
AU  - Krueger,Michael J
AU  - Mangubat-Medina,Alicia E
AU  - Ball,Zachary T
AU  - Sumazin,Pavel
AU  - Walker,Sarah R
AU  - Hamada,Yoshimasa
AU  - Oyadomari,Seiichi
AU  - Redell,Michele S
AU  - Frank,David A
TI  - Atovaquone is active against AML by upregulating the integrated stress pathway and suppressing oxidative phosphorylation
SN  - 2473-9537
PY  - 2020///0915
KW  - Activating Transcription Factor 4
KW  - metabolism
KW  - Adolescent
KW  - Animals
KW  - Apoptosis
KW  - drug effects
KW  - Atovaquone
KW  - pharmacology
KW  - Cell Line, Tumor
KW  - Cell Survival
KW  - Child
KW  - Child, Preschool
KW  - Disease Models, Animal
KW  - Female
KW  - Humans
KW  - Infant
KW  - Leukemia, Myeloid, Acute
KW  - genetics
KW  - Male
KW  - Mice
KW  - Mice, Knockout
KW  - Oxidative Phosphorylation
KW  - Signal Transduction
KW  - Xenograft Model Antitumor Assays
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S
UR  - https://doi.org/10.1182/bloodadvances.2019000499
ER  -