TY  - GEN
AU  - Le,Philipp
AU  - Kunold,Elena
AU  - Macsics,Robert
AU  - Rox,Katharina
AU  - Jennings,Megan C
AU  - Ugur,Ilke
AU  - Reinecke,Maria
AU  - Chaves-Moreno,Diego
AU  - Hackl,Mathias W
AU  - Fetzer,Christian
AU  - Mandl,Franziska A M
AU  - Lehmann,Johannes
AU  - Korotkov,Vadim S
AU  - Hacker,Stephan M
AU  - Kuster,Bernhard
AU  - Antes,Iris
AU  - Pieper,Dietmar H
AU  - Rohde,Manfred
AU  - Wuest,William M
AU  - Medina,Eva
AU  - Sieber,Stephan A
TI  - Repurposing human kinase inhibitors to create an antibiotic active against drug-resistant Staphylococcus aureus, persisters and biofilms
SN  - 1755-4349
PY  - 2020///0817
KW  - Animals
KW  - Anti-Bacterial Agents
KW  - chemical synthesis
KW  - Autolysis
KW  - chemically induced
KW  - Benzodioxoles
KW  - Biofilms
KW  - drug effects
KW  - Cell Line, Tumor
KW  - Drug Repositioning
KW  - Female
KW  - Humans
KW  - Male
KW  - Methicillin-Resistant Staphylococcus aureus
KW  - Mice, Inbred C57BL
KW  - Microbial Sensitivity Tests
KW  - Molecular Dynamics Simulation
KW  - Molecular Structure
KW  - Protein Kinase Inhibitors
KW  - chemistry
KW  - Sorafenib
KW  - analogs & derivatives
KW  - Structure-Activity Relationship
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S
UR  - https://doi.org/10.1038/s41557-019-0378-7
ER  -