TY - GEN AU - Maiti,Panchanan AU - Plemmons,Alexandra AU - Dunbar,Gary L TI - Combination treatment of berberine and solid lipid curcumin particles increased cell death and inhibited PI3K/Akt/mTOR pathway of human cultured glioblastoma cells more effectively than did individual treatments SN - 1932-6203 PY - 2020///0406 KW - Antineoplastic Combined Chemotherapy Protocols KW - administration & dosage KW - Apoptosis KW - drug effects KW - Berberine KW - Biological Availability KW - Brain Neoplasms KW - drug therapy KW - Cell Line, Tumor KW - Cell Proliferation KW - Cell Survival KW - Curcumin KW - Drug Carriers KW - chemistry KW - Drug Resistance, Neoplasm KW - Drug Screening Assays, Antitumor KW - Drug Synergism KW - Glioblastoma KW - Humans KW - Lipids KW - Phosphatidylinositol 3-Kinases KW - metabolism KW - Proto-Oncogene Proteins c-akt KW - Signal Transduction KW - TOR Serine-Threonine Kinases N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.pone.0225660 ER -