TY - GEN AU - Henkel,Matthew AU - Partyka,Jessica AU - Gregory,Alyssa D AU - Forno,Erick AU - Cho,Michael H AU - Eddens,Taylor AU - Tout,Andrew R AU - Salamacha,Nathan AU - Horne,William AU - Rao,Krithika S AU - Wu,Yijen AU - Alcorn,John F AU - Kostka,Dennis AU - Hirsch,Raphael AU - Celedón,Juan C AU - Shapiro,Steven D AU - Kolls,Jay K AU - Campfield,Brian T TI - FSTL-1 Attenuation Causes Spontaneous Smoke-Resistant Pulmonary Emphysema SN - 1535-4970 PY - 2020///0629 KW - Animals KW - Endothelial Cells KW - metabolism KW - Follistatin-Related Proteins KW - genetics KW - Gene Expression Regulation KW - Gene Knockdown Techniques KW - Humans KW - In Vitro Techniques KW - Lung KW - diagnostic imaging KW - Macrophages KW - drug effects KW - Mice KW - Mutation KW - Nuclear Receptor Subfamily 4, Group A, Member 1 KW - Phosphorylation KW - Polymorphism, Single Nucleotide KW - Positron Emission Tomography Computed Tomography KW - Pulmonary Disease, Chronic Obstructive KW - Pulmonary Emphysema KW - Single Photon Emission Computed Tomography Computed Tomography KW - Smoke KW - adverse effects KW - Nicotiana KW - Transcription Factor RelA KW - X-Ray Microtomography N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1164/rccm.201905-0973OC ER -