Low doses of BPA induced abnormal mitochondrial fission and hypertrophy in human embryonic stem cell-derived cardiomyocytes via the calcineurin-DRP1 signaling pathway: A comparison between XX and XY cardiomyocytes. [electronic resource]
- Toxicology and applied pharmacology 02 2020
- 114850 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1096-0333
10.1016/j.taap.2019.114850 doi
Benzhydryl Compounds--toxicity Calcineurin--genetics Cardiomyopathy, Hypertrophic--chemically induced Cell Differentiation Dose-Response Relationship, Drug Dynamins--metabolism Estrogens, Non-Steroidal--toxicity Gene Knockdown Techniques Human Embryonic Stem Cells--physiology Humans Karyotype Membrane Potential, Mitochondrial--drug effects Mitochondria--drug effects Mitochondrial Dynamics--drug effects Myocytes, Cardiac--cytology Phenols--toxicity RNA, Small Interfering--metabolism Sex Factors Signal Transduction--drug effects