Wyatt, Ryan M <br/><br/>
Pharmacologic Characterization of JNJ-42226314, [1-(4-Fluorophenyl)indol-5-yl]-[3-[4-(thiazole-2-carbonyl)piperazin-1-yl]azetidin-1-yl]methanone, a Reversible, Selective, and Potent Monoacylglycerol Lipase Inhibitor.  [electronic resource] 

 -  The Journal of pharmacology and experimental therapeutics  03 2020 
 - 339-353 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1521-0103 
<br/><br/><label>Standard No.: </label>10.1124/jpet.119.262139  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Binding, Competitive<br/>Brain--drug effects<br/>Dose-Response Relationship, Drug<br/>Enzyme Inhibitors--blood<br/>Escherichia coli--enzymology<br/>HeLa Cells<br/>Humans<br/>Kinetics<br/>Leukocytes, Mononuclear--drug effects<br/>Male<br/>Mice, Inbred C57BL<br/>Molecular Structure<br/>Monoacylglycerol Lipases--antagonists & inhibitors<br/>Pain--drug therapy<br/>Piperazines--blood<br/>Protein Binding<br/>Rats, Sprague-Dawley<br/>Receptor, Cannabinoid, CB1--agonists<br/>Receptor, Cannabinoid, CB2--agonists<br/>Sleep, REM--drug effects<br/>Substrate Specificity