TY  - GEN
AU  - Sprague-Piercy,Marc A
AU  - Wong,Eric
AU  - Roskamp,Kyle W
AU  - Fakhoury,Joseph N
AU  - Freites,J Alfredo
AU  - Tobias,Douglas J
AU  - Martin,Rachel W
TI  - Human αB-crystallin discriminates between aggregation-prone and function-preserving variants of a client protein
SN  - 1872-8006
PY  - 2020///0828
KW  - Cataract
KW  - genetics
KW  - Humans
KW  - Hydrophobic and Hydrophilic Interactions
KW  - Lens, Crystalline
KW  - metabolism
KW  - Molecular Chaperones
KW  - Molecular Dynamics Simulation
KW  - Mutation
KW  - Protein Binding
KW  - Protein Conformation
KW  - Protein Folding
KW  - Structure-Activity Relationship
KW  - alpha-Crystallin B Chain
KW  - gamma-Crystallins
KW  - chemistry
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S
UR  - https://doi.org/10.1016/j.bbagen.2019.129502
ER  -