TY - GEN AU - Hao,Gangping AU - Zhai,Jing AU - Jiang,Hanming AU - Zhang,Yuanying AU - Wu,Mengdi AU - Qiu,Yuyu AU - Fan,Cundong AU - Yu,Lijuan AU - Bai,Suyun AU - Sun,Lingyun AU - Yang,Zhongfa TI - Acetylshikonin induces apoptosis of human leukemia cell line K562 by inducing S phase cell cycle arrest, modulating ROS accumulation, depleting Bcr-Abl and blocking NF-κB signaling SN - 1950-6007 PY - 2020///0929 KW - Animals KW - Anthraquinones KW - pharmacology KW - Apoptosis KW - drug effects KW - Apoptosis Regulatory Proteins KW - metabolism KW - Cell Cycle KW - Cell Line KW - Cell Proliferation KW - Chlorocebus aethiops KW - Fusion Proteins, bcr-abl KW - Humans KW - K562 Cells KW - Leukemia, Myelogenous, Chronic, BCR-ABL Positive KW - drug therapy KW - Mitochondria KW - Protein Serine-Threonine Kinases KW - Reactive Oxygen Species KW - Signal Transduction KW - Vero Cells KW - NF-kappaB-Inducing Kinase N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.biopha.2019.109677 ER -