Hao, Gangping <br/><br/>
Acetylshikonin induces apoptosis of human leukemia cell line K562 by inducing S phase cell cycle arrest, modulating ROS accumulation, depleting Bcr-Abl and blocking NF-κB signaling.  [electronic resource] 

 -  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie  Feb 2020 
 - 109677 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1950-6007 
<br/><br/><label>Standard No.: </label>10.1016/j.biopha.2019.109677  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Anthraquinones--pharmacology<br/>Apoptosis--drug effects<br/>Apoptosis Regulatory Proteins--metabolism<br/>Cell Cycle--drug effects<br/>Cell Line<br/>Cell Proliferation--drug effects<br/>Chlorocebus aethiops<br/>Fusion Proteins, bcr-abl--metabolism<br/>Humans<br/>K562 Cells<br/>Leukemia, Myelogenous, Chronic, BCR-ABL Positive--drug therapy<br/>Mitochondria--drug effects<br/>Protein Serine-Threonine Kinases--metabolism<br/>Reactive Oxygen Species--metabolism<br/>Signal Transduction--drug effects<br/>Vero Cells<br/>NF-kappaB-Inducing Kinase