TY  - GEN
AU  - Panda,Subhankar
AU  - Pradhan,Nirmalya
AU  - Chatterjee,Soumya
AU  - Morla,Sudhir
AU  - Saha,Abhishek
AU  - Roy,Ashalata
AU  - Kumar,Sachin
AU  - Bhattacharyya,Arindam
AU  - Manna,Debasis
TI  - 4,5-Disubstituted 1,2,3-triazoles: Effective Inhibition of Indoleamine 2,3-Dioxygenase 1 Enzyme Regulates T cell Activity and Mitigates Tumor Growth
SN  - 2045-2322
PY  - 2020///1111
KW  - Animals
KW  - Antineoplastic Agents, Immunological
KW  - chemistry
KW  - Breast Neoplasms
KW  - drug therapy
KW  - Carcinoma, Ehrlich Tumor
KW  - Cell Line, Tumor
KW  - Drug Screening Assays, Antitumor
KW  - Enzyme Assays
KW  - Female
KW  - HEK293 Cells
KW  - Humans
KW  - Indoleamine-Pyrrole 2,3,-Dioxygenase
KW  - antagonists & inhibitors
KW  - Inhibitory Concentration 50
KW  - Kynurenine
KW  - immunology
KW  - Metabolic Networks and Pathways
KW  - drug effects
KW  - Mice
KW  - Molecular Docking Simulation
KW  - Primary Cell Culture
KW  - Recombinant Proteins
KW  - T-Lymphocytes, Cytotoxic
KW  - Triazoles
KW  - Tryptophan
KW  - Tryptophan Oxygenase
KW  - Tumor Escape
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/s41598-019-54963-9
ER  -