Panda, Subhankar <br/><br/>
4,5-Disubstituted 1,2,3-triazoles: Effective Inhibition of Indoleamine 2,3-Dioxygenase 1 Enzyme Regulates T cell Activity and Mitigates Tumor Growth.  [electronic resource] 

 -  Scientific reports  12 2019 
 - 18455 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>2045-2322 
<br/><br/><label>Standard No.: </label>10.1038/s41598-019-54963-9  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antineoplastic Agents, Immunological--chemistry<br/>Breast Neoplasms--drug therapy<br/>Carcinoma, Ehrlich Tumor--drug therapy<br/>Cell Line, Tumor<br/>Drug Screening Assays, Antitumor<br/>Enzyme Assays<br/>Female<br/>HEK293 Cells<br/>Humans<br/>Indoleamine-Pyrrole 2,3,-Dioxygenase--antagonists & inhibitors<br/>Inhibitory Concentration 50<br/>Kynurenine--immunology<br/>Metabolic Networks and Pathways--drug effects<br/>Mice<br/>Molecular Docking Simulation<br/>Primary Cell Culture<br/>Recombinant Proteins--chemistry<br/>T-Lymphocytes, Cytotoxic--drug effects<br/>Triazoles--chemistry<br/>Tryptophan--immunology<br/>Tryptophan Oxygenase--antagonists & inhibitors<br/>Tumor Escape--drug effects