TY - GEN AU - Hsu,Jessie Hao-Ru AU - Rasmusson,Timothy AU - Robinson,James AU - Pachl,Fiona AU - Read,Jon AU - Kawatkar,Sameer AU - O' Donovan,Daniel H AU - Bagal,Sharan AU - Code,Erin AU - Rawlins,Philip AU - Argyrou,Argyrides AU - Tomlinson,Ronald AU - Gao,Ning AU - Zhu,Xiahui AU - Chiarparin,Elisabetta AU - Jacques,Kelly AU - Shen,Minhui AU - Woods,Haley AU - Bednarski,Emma AU - Wilson,David M AU - Drew,Lisa AU - Castaldi,M Paola AU - Fawell,Stephen AU - Bloecher,Andrew TI - EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex SN - 2451-9448 PY - 2021///0315 KW - Cell Line, Tumor KW - Cell Proliferation KW - drug effects KW - Dose-Response Relationship, Drug KW - Enzyme Inhibitors KW - chemistry KW - Humans KW - Molecular Structure KW - Polycomb Repressive Complex 2 KW - antagonists & inhibitors KW - Proteolysis KW - Structure-Activity Relationship N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.chembiol.2019.11.004 ER -