Ghezzi, Chiara

A high-throughput screen identifies that CDK7 activates glucose consumption in lung cancer cells. [electronic resource] - Nature communications 11 2019 - 5444 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

2041-1723

10.1038/s41467-019-13334-8 doi


A549 Cells
Carcinoma, Non-Small-Cell Lung--metabolism
Cell Line, Tumor
Class I Phosphatidylinositol 3-Kinases--drug effects
Cyclin-Dependent Kinases--antagonists & inhibitors
Glucose--metabolism
Glucose Transporter Type 1--drug effects
High-Throughput Screening Assays
Humans
Lung Neoplasms--metabolism
Phenylenediamines--pharmacology
Phosphorylation
Protein Kinase Inhibitors--pharmacology
Pyrazoles--pharmacology
Pyrimidines--pharmacology
Quinazolines--pharmacology
RNA Polymerase II--drug effects
RNA, Messenger--metabolism
Signal Transduction
Triazines--pharmacology
Cyclin-Dependent Kinase-Activating Kinase