TY - GEN AU - Palomo,Marta AU - Vera,Manel AU - Martin,Susana AU - Torramadé-Moix,Sergi AU - Martinez-Sanchez,Julia AU - Belen Moreno,Ana AU - Carreras,Enric AU - Escolar,Ginés AU - Cases,Aleix AU - Díaz-Ricart,Maribel TI - Up-regulation of HDACs, a harbinger of uraemic endothelial dysfunction, is prevented by defibrotide SN - 1582-4934 PY - 2021///0422 KW - Case-Control Studies KW - Cell Nucleus KW - drug effects KW - Endothelium KW - Female KW - Histone Deacetylases KW - metabolism KW - Human Umbilical Vein Endothelial Cells KW - Humans KW - Intercellular Adhesion Molecule-1 KW - Male KW - Middle Aged KW - Phosphatidylinositol 3-Kinases KW - Polydeoxyribonucleotides KW - pharmacology KW - Proto-Oncogene Proteins c-akt KW - Reactive Oxygen Species KW - Renal Insufficiency, Chronic KW - blood KW - Signal Transduction KW - Toll-Like Receptor 4 KW - Up-Regulation KW - Uremia KW - von Willebrand Factor N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1111/jcmm.14865 ER -