Therapeutic strategies for diffuse midline glioma from high-throughput combination drug screening. [electronic resource]
- Science translational medicine 11 2019
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
1946-6242
10.1126/scitranslmed.aaw0064 doi
Animals Brain Neoplasms--drug therapy Brain Stem Neoplasms--drug therapy Cell Death Cell Line, Tumor Drug Evaluation, Preclinical Drug Synergism Female Glioma--drug therapy High-Throughput Screening Assays--methods Humans Lactones--pharmacology Male Metabolomics Mice Panobinostat--pharmacology Pyrroles--pharmacology Reproducibility of Results Sequence Analysis, RNA Transcription, Genetic--drug effects Xenograft Model Antitumor Assays