TY  - GEN
AU  - Jardine,Sasha
AU  - Anderson,Sierra
AU  - Babcock,Stephen
AU  - Leung,Gabriella
AU  - Pan,Jie
AU  - Dhingani,Neel
AU  - Warner,Neil
AU  - Guo,Conghui
AU  - Siddiqui,Iram
AU  - Kotlarz,Daniel
AU  - Dowling,James J
AU  - Melnyk,Roman A
AU  - Snapper,Scott B
AU  - Klein,Christoph
AU  - Thiagarajah,Jay R
AU  - Muise,Aleixo M
TI  - Drug Screen Identifies Leflunomide for Treatment of Inflammatory Bowel Disease Caused by TTC7A Deficiency
SN  - 1528-0012
PY  - 2020///0428
KW  - Adaptor Proteins, Signal Transducing
KW  - metabolism
KW  - Animals
KW  - Apoptosis
KW  - drug effects
KW  - Apoptosis Regulatory Proteins
KW  - Colon
KW  - cytology
KW  - Enzyme Inhibitors
KW  - pharmacology
KW  - Gene Knockout Techniques
KW  - Haploidy
KW  - Humans
KW  - Inflammatory Bowel Diseases
KW  - drug therapy
KW  - Leflunomide
KW  - Phosphorylation
KW  - Proteins
KW  - genetics
KW  - X-Linked Inhibitor of Apoptosis Protein
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1053/j.gastro.2019.11.019
ER  -