TY - GEN AU - Gerber,David E AU - Camidge,D Ross AU - Morgensztern,Daniel AU - Cetnar,Jeremey AU - Kelly,Ronan J AU - Ramalingam,Suresh S AU - Spigel,David R AU - Jeong,Woondong AU - Scaglioni,Pier P AU - Zhang,Song AU - Li,Marilyn AU - Weaver,David T AU - Vaikus,Louis AU - Keegan,Mitchell AU - Horobin,Joanna C AU - Burns,Timothy F TI - Phase 2 study of the focal adhesion kinase inhibitor defactinib (VS-6063) in previously treated advanced KRAS mutant non-small cell lung cancer SN - 1872-8332 PY - 2020///1230 KW - Adenocarcinoma of Lung KW - drug therapy KW - Benzamides KW - therapeutic use KW - Carcinoma, Non-Small-Cell Lung KW - Drug Resistance, Neoplasm KW - drug effects KW - Female KW - Focal Adhesion Protein-Tyrosine Kinases KW - antagonists & inhibitors KW - Follow-Up Studies KW - Humans KW - Lung Neoplasms KW - Male KW - Middle Aged KW - Mutation KW - Prognosis KW - Prospective Studies KW - Proto-Oncogene Proteins p21(ras) KW - genetics KW - Pyrazines KW - Salvage Therapy KW - Sulfonamides KW - Survival Rate N1 - Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1016/j.lungcan.2019.10.033 ER -