Gerber, David E

Phase 2 study of the focal adhesion kinase inhibitor defactinib (VS-6063) in previously treated advanced KRAS mutant non-small cell lung cancer. [electronic resource] - Lung cancer (Amsterdam, Netherlands) 01 2020 - 60-67 p. digital

Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

1872-8332

10.1016/j.lungcan.2019.10.033 doi


Adenocarcinoma of Lung--drug therapy
Benzamides--therapeutic use
Carcinoma, Non-Small-Cell Lung--drug therapy
Drug Resistance, Neoplasm--drug effects
Female
Focal Adhesion Protein-Tyrosine Kinases--antagonists & inhibitors
Follow-Up Studies
Humans
Lung Neoplasms--drug therapy
Male
Middle Aged
Mutation
Prognosis
Prospective Studies
Proto-Oncogene Proteins p21(ras)--genetics
Pyrazines--therapeutic use
Salvage Therapy
Sulfonamides--therapeutic use
Survival Rate