Phase 2 study of the focal adhesion kinase inhibitor defactinib (VS-6063) in previously treated advanced KRAS mutant non-small cell lung cancer. [electronic resource]
- Lung cancer (Amsterdam, Netherlands) 01 2020
- 60-67 p. digital
Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
1872-8332
10.1016/j.lungcan.2019.10.033 doi
Adenocarcinoma of Lung--drug therapy Benzamides--therapeutic use Carcinoma, Non-Small-Cell Lung--drug therapy Drug Resistance, Neoplasm--drug effects Female Focal Adhesion Protein-Tyrosine Kinases--antagonists & inhibitors Follow-Up Studies Humans Lung Neoplasms--drug therapy Male Middle Aged Mutation Prognosis Prospective Studies Proto-Oncogene Proteins p21(ras)--genetics Pyrazines--therapeutic use Salvage Therapy Sulfonamides--therapeutic use Survival Rate