Metselaar, Dennis S <br/><br/>
Celastrol-induced degradation of FANCD2 sensitizes pediatric high-grade gliomas to the DNA-crosslinking agent carboplatin.  [electronic resource] 

 -  EBioMedicine  Dec 2019 
 - 81-92 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>2352-3964 
<br/><br/><label>Standard No.: </label>10.1016/j.ebiom.2019.10.062  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adolescent<br/>Animals<br/>Carboplatin--pharmacology<br/>Cell Line, Tumor<br/>Cell Survival--drug effects<br/>Child<br/>Child, Preschool<br/>Cross-Linking Reagents--pharmacology<br/>DNA Damage<br/>Disease Models, Animal<br/>Drug Resistance, Neoplasm--genetics<br/>Fanconi Anemia Complementation Group D2 Protein--genetics<br/>Female<br/>Glioma--genetics<br/>Humans<br/>Male<br/>Mice<br/>Neoplasm Grading<br/>Pentacyclic Triterpenes<br/>Proteolysis--drug effects<br/>Triterpenes--pharmacology<br/>Xenograft Model Antitumor Assays