Botros, Sanaa S <br/><br/>
The phosphodiesterase-4 inhibitor roflumilast impacts Schistosoma mansoni ovipositing in vitro but displays only modest antischistosomal activity in vivo.  [electronic resource] 

 -  Experimental parasitology  Jan 2020 
 - 107793 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1090-2449 
<br/><br/><label>Standard No.: </label>10.1016/j.exppara.2019.107793  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Aminopyridines--pharmacology<br/>Animals<br/>Anthelmintics--pharmacology<br/>Benzamides--pharmacology<br/>Cyclic Nucleotide Phosphodiesterases, Type 1--antagonists & inhibitors<br/>Cyclopropanes--pharmacology<br/>Dose-Response Relationship, Drug<br/>Female<br/>Inhibitory Concentration 50<br/>Male<br/>Mice<br/>Microscopy, Electron, Scanning<br/>Oviposition--drug effects<br/>Phosphodiesterase 4 Inhibitors--pharmacology<br/>Praziquantel--pharmacology<br/>Schistosoma mansoni--drug effects