TY - GEN AU - Yeong,Keng Yoon AU - Khaw,Kooi Yeong AU - Takahashi,Yukari AU - Itoh,Yukihiro AU - Murugaiyah,Vikneswaran AU - Suzuki,Takayoshi TI - Discovery of gamma-mangostin from Garcinia mangostana as a potent and selective natural SIRT2 inhibitor SN - 1090-2120 PY - 2021///0217 KW - Antineoplastic Agents, Phytogenic KW - chemistry KW - Cell Proliferation KW - drug effects KW - Dose-Response Relationship, Drug KW - Drug Discovery KW - Drug Screening Assays, Antitumor KW - Enzyme Inhibitors KW - Garcinia mangostana KW - Humans KW - Molecular Docking Simulation KW - Molecular Structure KW - Sirtuin 2 KW - antagonists & inhibitors KW - Structure-Activity Relationship KW - Tumor Cells, Cultured KW - Xanthones N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.bioorg.2019.103403 ER -