Galectin-1-driven T cell exclusion in the tumor endothelium promotes immunotherapy resistance. [electronic resource]
- The Journal of clinical investigation 12 2019
- 5553-5567 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1558-8238
10.1172/JCI129025 doi
Adult Aged Aged, 80 and over Animals B7-H1 Antigen--antagonists & inhibitors Endothelium--physiology Female Galectin 1--antagonists & inhibitors Galectins--physiology Head and Neck Neoplasms--drug therapy Humans Immune Tolerance Immunotherapy Male Mice Mice, Inbred C57BL Middle Aged Programmed Cell Death 1 Receptor--antagonists & inhibitors STAT1 Transcription Factor--physiology T-Lymphocytes--immunology