Jiang, Ying

Tanshinone IIA ameliorates the bleomycin-induced endothelial-to-mesenchymal transition via the Akt/mTOR/p70S6K pathway in a murine model of systemic sclerosis. [electronic resource] - International immunopharmacology Dec 2019 - 105968 p. digital

Publication Type: Journal Article

1878-1705

10.1016/j.intimp.2019.105968 doi


Abietanes--pharmacology
Animals
Bleomycin--pharmacology
Cell Line
Disease Models, Animal
Endothelial Cells--drug effects
Endothelium--drug effects
Epithelial-Mesenchymal Transition--drug effects
Female
Fibrosis--drug therapy
Human Umbilical Vein Endothelial Cells
Humans
Mice
Mice, Inbred C57BL
Proto-Oncogene Proteins c-akt--metabolism
Ribosomal Protein S6 Kinases, 70-kDa--metabolism
Salvia miltiorrhiza--chemistry
Scleroderma, Systemic--metabolism
Signal Transduction--drug effects
TOR Serine-Threonine Kinases--metabolism