Zhu, Haizhou <br/><br/>
Oxidative Cyclization-Induced Activation of a Phosphoinositide 3-Kinase Inhibitor for Enhanced Selectivity of Cancer Chemotherapeutics.  [electronic resource] 

 -  ChemMedChem  11 2019 
 - 1933-1939 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S. 
<br/><br/><label>ISSN: </label>1860-7187 
<br/><br/><label>Standard No.: </label>10.1002/cmdc.201900481  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antineoplastic Agents--chemical synthesis<br/>Cell Line<br/>Cell Proliferation--drug effects<br/>Cell Survival--drug effects<br/>Cyclization<br/>Dose-Response Relationship, Drug<br/>Drug Screening Assays, Antitumor<br/>Humans<br/>Microsomes, Liver--chemistry<br/>Molecular Structure<br/>Oxidation-Reduction<br/>Phosphatidylinositol 3-Kinases--metabolism<br/>Protein Kinase Inhibitors--chemical synthesis<br/>Reactive Oxygen Species--analysis<br/>Structure-Activity Relationship