TY - GEN AU - Cáceres,Felipe Tapia AU - Gaspari,Tracey A AU - Samuel,Chrishan S AU - Pinar,Anita A TI - Serelaxin inhibits the profibrotic TGF-β1/IL-1β axis by targeting TLR-4 and the NLRP3 inflammasome in cardiac myofibroblasts SN - 1530-6860 PY - 2020///0615 KW - Animals KW - Cells, Cultured KW - Fibrosis KW - Humans KW - Inflammasomes KW - metabolism KW - Interleukin-1beta KW - Male KW - Mice KW - Myocardium KW - cytology KW - Myofibroblasts KW - drug effects KW - NLR Family, Pyrin Domain-Containing 3 Protein KW - Recombinant Proteins KW - pharmacology KW - Relaxin KW - Toll-Like Receptor 4 KW - Transforming Growth Factor beta1 N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1096/fj.201901079RR ER -