TY - GEN AU - Millard,Louise A C AU - Munafò,Marcus R AU - Tilling,Kate AU - Wootton,Robyn E AU - Davey Smith,George TI - MR-pheWAS with stratification and interaction: Searching for the causal effects of smoking heaviness identified an effect on facial aging SN - 1553-7404 PY - 2020///0129 KW - Biological Specimen Banks KW - Cigarette Smoking KW - adverse effects KW - Computational Biology KW - methods KW - Gene-Environment Interaction KW - Genetic Pleiotropy KW - Humans KW - Male KW - Mendelian Randomization Analysis KW - Middle Aged KW - Polymorphism, Single Nucleotide KW - Proof of Concept Study KW - Skin Aging KW - drug effects KW - United Kingdom KW - epidemiology N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.pgen.1008353 ER -