Michaelis, Katherine A <br/><br/>
The TLR7/8 agonist R848 remodels tumor and host responses to promote survival in pancreatic cancer.  [electronic resource] 

 -  Nature communications  10 2019 
 - 4682 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>2041-1723 
<br/><br/><label>Standard No.: </label>10.1038/s41467-019-12657-w  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Body Weight--drug effects<br/>CD8-Positive T-Lymphocytes--immunology<br/>Cachexia<br/>Carcinoma, Pancreatic Ductal--genetics<br/>Cell Line, Tumor<br/>Eating--drug effects<br/>Gene Expression<br/>Humans<br/>Imidazoles--pharmacology<br/>Locomotion--drug effects<br/>Mice<br/>Mice, Knockout<br/>Pancreatic Intraductal Neoplasms--genetics<br/>Pancreatic Neoplasms--genetics<br/>Sequence Analysis, RNA<br/>Survival Rate<br/>Toll-Like Receptor 7--agonists<br/>Toll-Like Receptor 8--agonists<br/>Tumor Burden<br/>Tumor Microenvironment--drug effects