Colasante, Gaia <br/><br/>
dCas9-Based Scn1a Gene Activation Restores Inhibitory Interneuron Excitability and Attenuates Seizures in Dravet Syndrome Mice.  [electronic resource] 

 -  Molecular therapy : the journal of the American Society of Gene Therapy  01 2020 
 - 235-253 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1525-0024 
<br/><br/><label>Standard No.: </label>10.1016/j.ymthe.2019.08.018  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Action Potentials<br/>Animals<br/>CRISPR-Associated Protein 9--genetics<br/>Cell Line, Tumor<br/>Disease Models, Animal<br/>Epilepsies, Myoclonic--therapy<br/>Female<br/>GABAergic Neurons--metabolism<br/>Genetic Therapy--methods<br/>Hippocampus--cytology<br/>Interneurons--metabolism<br/>Mice<br/>Mice, Inbred C57BL<br/>Mice, Transgenic<br/>NAV1.1 Voltage-Gated Sodium Channel--genetics<br/>Seizures--therapy<br/>Transcriptional Activation<br/>Treatment Outcome