The R882H DNMT3A hot spot mutation stabilizes the formation of large DNMT3A oligomers with low DNA methyltransferase activity. [electronic resource]
- The Journal of biological chemistry 11 2019
- 16966-16977 p. digital
Publication Type: Journal Article
1083-351X
10.1074/jbc.RA119.010126 doi
DNA--metabolism DNA (Cytosine-5-)-Methyltransferases--chemistry DNA Methyltransferase 3A Humans Models, Molecular Mutation Protein Multimerization Protein Structure, Quaternary