TY - GEN AU - Kopetz,Scott AU - Grothey,Axel AU - Yaeger,Rona AU - Van Cutsem,Eric AU - Desai,Jayesh AU - Yoshino,Takayuki AU - Wasan,Harpreet AU - Ciardiello,Fortunato AU - Loupakis,Fotios AU - Hong,Yong Sang AU - Steeghs,Neeltje AU - Guren,Tormod K AU - Arkenau,Hendrik-Tobias AU - Garcia-Alfonso,Pilar AU - Pfeiffer,Per AU - Orlov,Sergey AU - Lonardi,Sara AU - Elez,Elena AU - Kim,Tae-Won AU - Schellens,Jan H M AU - Guo,Christina AU - Krishnan,Asha AU - Dekervel,Jeroen AU - Morris,Van AU - Calvo Ferrandiz,Aitana AU - Tarpgaard,L S AU - Braun,Michael AU - Gollerkeri,Ashwin AU - Keir,Christopher AU - Maharry,Kati AU - Pickard,Michael AU - Christy-Bittel,Janna AU - Anderson,Lisa AU - Sandor,Victor AU - Tabernero,Josep TI - Encorafenib, Binimetinib, and Cetuximab in SN - 1533-4406 PY - 2019///1106 KW - Adult KW - Aged KW - Aged, 80 and over KW - Antineoplastic Combined Chemotherapy Protocols KW - adverse effects KW - Benzimidazoles KW - administration & dosage KW - Carbamates KW - Cetuximab KW - Colorectal Neoplasms KW - drug therapy KW - Disease Progression KW - Electrocorticography KW - Female KW - Humans KW - Intention to Treat Analysis KW - Irinotecan KW - therapeutic use KW - Kaplan-Meier Estimate KW - Male KW - Middle Aged KW - Mutation KW - Proto-Oncogene Proteins B-raf KW - genetics KW - Sulfonamides KW - Survival Analysis N1 - Publication Type: Clinical Trial, Phase III; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1056/NEJMoa1908075 ER -