TY - GEN AU - Shimamatsu,Junichiro AU - Sasaki,Ken-Ichiro AU - Katsuki,Yoshio AU - Kawasaki,Tomohiro AU - Murasato,Yoshinobu AU - Ajisaka,Hidehiko AU - Yokoi,Hiroyoshi AU - Tashiro,Hideki AU - Harada,Atsushi AU - Hirakawa,Yuji AU - Ishizaki,Yuta AU - Ishimatsu,Takashi AU - Kagiyama,Kotaro AU - Fukumoto,Yoshihiro AU - Kakuma,Tatsuyuki AU - Ueno,Takafumi TI - Prasugrel effectively reduces the platelet reactivity units in patients with genetically metabolic dysfunction of cytochrome P450 2C19 who are treated with long-term dual antiplatelet therapy after undergoing drug-eluting stent implantation SN - 1615-2573 PY - 2020///1026 KW - Adult KW - Aged KW - Aged, 80 and over KW - Aspirin KW - administration & dosage KW - Clopidogrel KW - Coronary Artery Disease KW - blood KW - Cytochrome P-450 CYP2C19 KW - genetics KW - Drug Resistance KW - Drug Substitution KW - adverse effects KW - Drug-Eluting Stents KW - Dual Anti-Platelet Therapy KW - Female KW - Humans KW - Japan KW - Male KW - Middle Aged KW - Percutaneous Coronary Intervention KW - Pharmacogenomic Variants KW - Platelet Aggregation KW - drug effects KW - Platelet Aggregation Inhibitors KW - Polymorphism, Single Nucleotide KW - Prasugrel Hydrochloride KW - Purinergic P2Y Receptor Antagonists KW - Risk Factors KW - Time Factors KW - Treatment Outcome N1 - Publication Type: Journal Article; Multicenter Study; Randomized Controlled Trial UR - https://doi.org/10.1007/s00380-019-01499-7 ER -