TY  - GEN
AU  - Wang,Daqi
AU  - Zhang,Chengdong
AU  - Wang,Bei
AU  - Li,Bin
AU  - Wang,Qiang
AU  - Liu,Dong
AU  - Wang,Hongyan
AU  - Zhou,Yan
AU  - Shi,Leming
AU  - Lan,Feng
AU  - Wang,Yongming
TI  - Optimized CRISPR guide RNA design for two high-fidelity Cas9 variants by deep learning
SN  - 2041-1723
PY  - 2020///0106
KW  - Animals
KW  - Base Sequence
KW  - genetics
KW  - CRISPR-Cas Systems
KW  - Cell Line, Tumor
KW  - Clustered Regularly Interspaced Short Palindromic Repeats
KW  - Deep Learning
KW  - Endonucleases
KW  - metabolism
KW  - Gene Editing
KW  - methods
KW  - HEK293 Cells
KW  - HeLa Cells
KW  - Humans
KW  - INDEL Mutation
KW  - Internet
KW  - Mice
KW  - Promoter Regions, Genetic
KW  - RNA, Guide, CRISPR-Cas Systems
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/s41467-019-12281-8
ER  -