TY - GEN AU - Bonnet,Caroline AU - Hao,Jizhe AU - Osorio,Nancy AU - Donnet,Anne AU - Penalba,Virginie AU - Ruel,Jérôme AU - Delmas,Patrick TI - Maladaptive activation of Nav1.9 channels by nitric oxide causes triptan-induced medication overuse headache SN - 2041-1723 PY - 2020///0103 KW - Animals KW - Calcitonin Gene-Related Peptide KW - metabolism KW - Cell Degranulation KW - physiology KW - Cells, Cultured KW - Female KW - Headache Disorders, Secondary KW - chemically induced KW - Hyperalgesia KW - physiopathology KW - Male KW - Mast Cells KW - pathology KW - Mice KW - Mice, Inbred C57BL KW - Mice, Knockout KW - Migraine Disorders KW - NAV1.9 Voltage-Gated Sodium Channel KW - genetics KW - Neurons, Afferent KW - drug effects KW - Nitric Oxide KW - Nociceptors KW - Pain KW - Prescription Drug Overuse KW - adverse effects KW - Tryptamines N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/s41467-019-12197-3 ER -