TY - GEN AU - Huang,Rong AU - Zong,Xiaohua AU - Nadesan,Puviindran AU - Huebner,Janet L AU - Kraus,Virginia B AU - White,James P AU - White,Phillip J AU - Baht,Gurpreet S TI - Lowering circulating apolipoprotein E levels improves aged bone fracture healing SN - 2379-3708 PY - 2020///0930 KW - Adult KW - Age Factors KW - Aged KW - Aged, 80 and over KW - Aging KW - blood KW - Animals KW - Apolipoproteins E KW - antagonists & inhibitors KW - Bony Callus KW - diagnostic imaging KW - Calcification, Physiologic KW - drug effects KW - Cell Differentiation KW - Cells, Cultured KW - Cohort Studies KW - Dependovirus KW - genetics KW - Disease Models, Animal KW - Female KW - Fracture Healing KW - Genetic Vectors KW - administration & dosage KW - Humans KW - Mice KW - Mice, Knockout, ApoE KW - Middle Aged KW - Osteoblasts KW - Primary Cell Culture KW - RNA, Small Interfering KW - Recombinant Proteins KW - Signal Transduction KW - Tibial Fractures KW - X-Ray Microtomography N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1172/jci.insight.129144 ER -