TY - GEN AU - Rovati,L C AU - Brambilla,N AU - Blicharski,T AU - Connell,J AU - Vitalini,C AU - Bonazzi,A AU - Giacovelli,G AU - Girolami,F AU - D'Amato,M TI - Efficacy and safety of the first-in-class imidazoline-2 receptor ligand CR4056 in pain from knee osteoarthritis and disease phenotypes: a randomized, double-blind, placebo-controlled phase 2 trial SN - 1522-9653 PY - 2021///0205 KW - Arthralgia KW - drug therapy KW - Double-Blind Method KW - Female KW - Humans KW - Imidazoles KW - adverse effects KW - Male KW - Middle Aged KW - Osteoarthritis, Knee KW - Pain Measurement KW - Proof of Concept Study KW - Quinazolines KW - Treatment Outcome N1 - Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.joca.2019.09.002 ER -