A small-sized protein binder specific for human PD-1 effectively suppresses the tumour growth in tumour mouse model. [electronic resource]
- Journal of drug targeting 04 2020
- 419-427 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1029-2330
10.1080/1061186X.2019.1669042 doi
Animals Antibodies, Monoclonal--pharmacology CHO Cells CTLA-4 Antigen--metabolism Cell Line Cell Proliferation--drug effects Cricetulus Disease Models, Animal Female Humans Immune Checkpoint Inhibitors--pharmacology Immunotherapy--methods Leukocytes, Mononuclear--drug effects Male Mice Mice, Inbred BALB C Mice, Inbred NOD Neoplasms--drug therapy Programmed Cell Death 1 Receptor--metabolism Protein Binding--drug effects T-Lymphocytes--drug effects