TY - GEN AU - Wang,Victoria E AU - Xue,Jenny Y AU - Frederick,Dennie T AU - Cao,Yi AU - Lin,Eva AU - Wilson,Catherine AU - Urisman,Anatoly AU - Carbone,David P AU - Flaherty,Keith T AU - Bernards,Rene AU - Lito,Piro AU - Settleman,Jeff AU - McCormick,Frank TI - Adaptive Resistance to Dual BRAF/MEK Inhibition in BRAF-Driven Tumors through Autocrine FGFR Pathway Activation SN - 1557-3265 PY - 2020///0921 KW - Animals KW - Antineoplastic Agents KW - pharmacology KW - Apoptosis KW - Autocrine Communication KW - Biomarkers, Tumor KW - metabolism KW - Carcinoma, Non-Small-Cell Lung KW - drug therapy KW - Cell Proliferation KW - Drug Resistance, Neoplasm KW - Fibroblast Growth Factor 1 KW - Gene Expression Regulation, Neoplastic KW - High-Throughput Screening Assays KW - Humans KW - Lung Neoplasms KW - MAP Kinase Kinase 1 KW - antagonists & inhibitors KW - Melanoma KW - Mice KW - Mice, Nude KW - Prognosis KW - Proto-Oncogene Proteins B-raf KW - Receptor, Fibroblast Growth Factor, Type 1 KW - Survival Rate KW - Tumor Cells, Cultured KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1158/1078-0432.CCR-18-2779 ER -