TY - GEN AU - Peter,Cyril J AU - Saito,Atsushi AU - Hasegawa,Yuto AU - Tanaka,Yuya AU - Nagpal,Mohika AU - Perez,Gabriel AU - Alway,Emily AU - Espeso-Gil,Sergio AU - Fayyad,Tariq AU - Ratner,Chana AU - Dincer,Aslihan AU - Gupta,Achla AU - Devi,Lakshmi AU - Pappas,John G AU - Lalonde,François M AU - Butman,John A AU - Han,Joan C AU - Akbarian,Schahram AU - Kamiya,Atsushi TI - In vivo epigenetic editing of Sema6a promoter reverses transcallosal dysconnectivity caused by C11orf46/Arl14ep risk gene SN - 2041-1723 PY - 2019///1223 KW - Adaptor Proteins, Vesicular Transport KW - genetics KW - Animals KW - Axons KW - metabolism KW - Corpus Callosum KW - Epigenesis, Genetic KW - Epigenome KW - Gene Editing KW - Gene Expression Regulation KW - Genetic Predisposition to Disease KW - HEK293 Cells KW - Histone-Lysine N-Methyltransferase KW - Humans KW - Mice, Inbred C57BL KW - Nerve Net KW - Neurites KW - Nuclear Proteins KW - Phenotype KW - Promoter Regions, Genetic KW - Protein Binding KW - Protein Methyltransferases KW - Semaphorins N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/s41467-019-12013-y ER -