TY - GEN AU - Wright,Thomas D AU - Raybuck,Christopher AU - Bhatt,Akshita AU - Monlish,Darlene AU - Chakrabarty,Suravi AU - Wendekier,Katy AU - Gartland,Nathan AU - Gupta,Mohit AU - Burow,Matthew E AU - Flaherty,Patrick T AU - Cavanaugh,Jane E TI - Pharmacological inhibition of the MEK5/ERK5 and PI3K/Akt signaling pathways synergistically reduces viability in triple-negative breast cancer SN - 1097-4644 PY - 2021///0129 KW - Apoptosis KW - drug effects KW - Benzodiazepinones KW - pharmacology KW - Cell Line, Tumor KW - Cell Movement KW - Cell Proliferation KW - Cell Survival KW - Drug Synergism KW - Female KW - Humans KW - MAP Kinase Kinase 5 KW - antagonists & inhibitors KW - Mitogen-Activated Protein Kinase 7 KW - Phosphatidylinositol 3-Kinases KW - metabolism KW - Phosphoinositide-3 Kinase Inhibitors KW - Piperazines KW - Proto-Oncogene Proteins c-akt KW - Pyridones KW - Pyrimidines KW - Pyrimidinones KW - Signal Transduction KW - Triple Negative Breast Neoplasms N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1002/jcb.29350 ER -