TY - GEN AU - Cao,Zhi-Xing AU - Wen,Yi AU - He,Jun-Lin AU - Huang,Shen-Zhen AU - Gao,Fei AU - Guo,Chuan-Jie AU - Liu,Qing-Qing AU - Zheng,Shu-Wen AU - Gong,Dao-Yin AU - Li,Yu-Zhi AU - Zhang,Ruo-Qi AU - Chen,Jian-Ping AU - Peng,Cheng TI - Isoliquiritigenin, an Orally Available Natural FLT3 Inhibitor from Licorice, Exhibits Selective Anti-Acute Myeloid Leukemia Efficacy In Vitro and In Vivo SN - 1521-0111 PY - 2020///0303 KW - Administration, Oral KW - Animals KW - Cell Line, Tumor KW - Cell Survival KW - drug effects KW - Chalcones KW - administration & dosage KW - Dose-Response Relationship, Drug KW - Enzyme Inhibitors KW - Female KW - Glycyrrhiza KW - Humans KW - Leukemia, Myeloid, Acute KW - drug therapy KW - Mice KW - Mice, Inbred NOD KW - Mice, SCID KW - Molecular Docking Simulation KW - methods KW - Treatment Outcome KW - Xenograft Model Antitumor Assays KW - fms-Like Tyrosine Kinase 3 KW - antagonists & inhibitors N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1124/mol.119.116129 ER -