TY - GEN AU - Chure,Griffin AU - Razo-Mejia,Manuel AU - Belliveau,Nathan M AU - Einav,Tal AU - Kaczmarek,Zofii A AU - Barnes,Stephanie L AU - Lewis,Mitchell AU - Phillips,Rob TI - Predictive shifts in free energy couple mutations to their phenotypic consequences SN - 1091-6490 PY - 2020///0326 KW - Algorithms KW - Allosteric Regulation KW - DNA-Binding Proteins KW - genetics KW - Energy Metabolism KW - Escherichia coli KW - Gene Dosage KW - Genetic Association Studies KW - Lac Repressors KW - Models, Biological KW - Mutation KW - Operator Regions, Genetic KW - Phenotype KW - Protein Interaction Domains and Motifs N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1073/pnas.1907869116 ER -