Predictive shifts in free energy couple mutations to their phenotypic consequences. [electronic resource]
- Proceedings of the National Academy of Sciences of the United States of America 09 2019
- 18275-18284 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1091-6490
10.1073/pnas.1907869116 doi
Algorithms Allosteric Regulation DNA-Binding Proteins--genetics Energy Metabolism--genetics Escherichia coli--genetics Gene Dosage Genetic Association Studies Lac Repressors--genetics Models, Biological Mutation Operator Regions, Genetic Phenotype Protein Interaction Domains and Motifs